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RECEPTOR, SEROTONIN, 5-HT1B
Descriptors Found:
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DeCS
Descriptor
English
:
Receptor, Serotonin, 5-HT1B
Descriptor
Spanish
:
Receptor de Serotonina 5-HT1B
Descriptor
Portuguese
:
Receptor 5-HT1B de Serotonina
Synonyms
English
:
Serotonin 1B Receptor
Tree Number:
D12.776.543.750.070.800.100.150
D12.776.543.750.100.800.100.150
D12.776.543.750.720.300.800.100.150
D12.776.543.750.720.670.100.500
Definition
English
:
A
serotonin
receptor subtype found at high levels in the
BASAL GANGLIA
and the frontal cortex. It plays a
role
as a terminal autoreceptor that regulates the rate of
SEROTONIN
release from
nerve endings
. This
serotonin
receptor subtype is closely related to and has
similar
drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist
SUMATRIPTAN
and may be involved in mediating the drug's antimigraine effect.
Entry Combination - descr/qualif
English
:
Receptor, Serotonin, 5-HT1B
/
agonists
use
Serotonin 5-HT1 Receptor Agonists
Receptor, Serotonin, 5-HT1B
/
antagonists & inhibitors
use
Serotonin 5-HT1 Receptor Antagonists
History Note
English
:
2004; use RECEPTOR, SEROTONIN, 5-HT1B (NM) 1993-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AN
analysis
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
38304
Unique Identifier:
D044302
Occurrence in VHL
:
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